The Rockies’ tough times just got tougher.

The club lost both right-handed starter Antonio Senzatela and right-fielder Charlie Blackmon to injuries early in its 13-0 loss to the Cardinals on Thursday afternoon at Busch Stadium.

Senzatela might have suffered a significant left knee injury but Blackmon’s injury to his right hamstring does not appear to be serious. 

Manager Bud Black told reporters in St. Louis after the game that he had “nothing concrete” to report but Black did say that Senzatela will undergo an MRI on his left knee on Friday.

“He definitely has a knee sprain, to a certain extent,” Black told AT&T SportsNet. “How significant we won’t know until we get the (MRI) tomorrow. Devastating, right? As of now, we are crossing our fingers, for sure.”

Senzatela was injured in the second inning when he tried to cover first base on Brendan Donovan’s infield single to Elehuris Montero. Senzatela pulled up lame and fell to the ground in obvious pain. clutching his left knee.

Senzatela was helped off the field and immediately taken to the clubhouse.

Left-hander Austin Gomber took over for Senzatela in a game the Cardinals were leading 5-0 in the second inning.

Blackmon beat out an infield hit in the first inning but ran gingerly as he approached the first-base bag. He stayed in the game through the Rockies’ at-bat but was removed from the game prior to the bottom of the second inning.

“I think Charlie is going to be fine,” Black said of the 36-year-old outfielder. “He’s been hit in the hamstring a couple of times with pitches. It tightened up three or four days ago when he was running.

“But I just spoke to Charlie and Charlie thinks he’s going to be fine. He probably won’t start (Friday) night and we’ll give him another day or two to see where he is. But this is not an injury-list situation at all for Chuck.”

After getting swept in the three-game series by the Cardinals, the Rockies return home to open a three-game series against San Francisco.